ID |
Refrence |
Source Clone name |
Sequence |
Motif |
Target-tumor |
Target-cell |
Receptors-biomarker |
Phage/Library |
In vitro/Ex-vivo |
In vivo |
Homing/targeting |
Payloads |
Patent |
1019 | Hassan S et al. Int J Cancer. 2011 Jul 1;129(1):225-32. | CTCE-9908 (Synthetic), dimer | KGVSLSYR | NA | Breast cancer | Endothelial cell | SDF-1/CXCR4 ligand/receptor pair | NA | NA | Tansgenic mouse model for breast cancer, mouse mammary tumor virus (MMTV)-driven Polyoma Middle T Antigen (PyMT) model | Homing | Docetaxel or DC101 (an anti-VEGFR2 monoclonal antibody) | US 2011/011 8193A1 |
1167 | Zhi M et al. Cancer Biol Ther. 2004 Dec;3(12):1232-5. | NA | CGNSNPKSC | NA | Gastric cancer | Endothelial cell | NA | T7 phage/C7C peptide library | Human umbilical vein endothelial cells( HUVEC), lovo cells, Hep-g2 cells, SGC-7901 cells, Eca-109 cells | 2 month old Balb/c mice of human xenograft of gastric cancer | Homing | NA | NA |
1168 | Zhi M et al. Cancer Biol Ther. 2004 Dec;3(12):1232-5. | NA | CPHNLTKLC | NA | Gastric cancer | Endothelial cell | NA | T7 phage/C7C peptide library | Human umbilical vein endothelial cells( HUVEC), lovo cells, Hep-g2 cells, SGC-7901 cells, Eca-109 cells | 2 month old Balb/c mice of human xenograft of gastric cancer | Homing (Phage display clone) | NA | NA |
1170 | Dickerson EB et al. Mol Cancer Res. 2004 Dec;2(12):663-73. | mrIL-12vp [mouse recombinant interleukin (IL)-12 | CDCRGDCFC | RGD | Tumor neovasculature | Endothelial cells | Alpha-5 beta-3 integrins | NA | M21 human melanoma cells, Saos-2 osteosarcoma cells | Mice injected with NXS2 neuroblastoma cells | Homing | mrIl-12vp peptide | US 2004/0131623A9 |
1176 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | RGR | CRGRRST | RGRRS, RGRR | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | WO05041882A2,US20050245445A1 |
1177 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | RSR | CRSRKG | CRSR-GCRSR-G | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | US 2005/0245445A1 |
1178 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | KAA | CKAAKNK | CKA-K | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | US 2005/0245445A1 |
1179 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | KAR | CKGAKAR | CKGAKA, AKAR, GAKAR | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | US 2010/0076175A1 |
1180 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | VGVA | FRVGVADV | F-VGVADV, RVGV | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | US 2005/0245445A1 |
1181 | Joyce JA et al. Cancer Cell. 2003 Nov;4(5):393-403. | EYQ | CEYQLDVE | CEYQL, YQLDV, YQLDV | Pancreatic islet carcinoma | Endothelial cellor pericytes | NA | T7 phage/CX7C peptide library | NA | Prototypical mouse model of multistage tumorigenesis, RIP1-Tag2 transgenic model of islet cell carcinoma and K14-HPV16 mice | Homing | NA | US 2005/0245445 A1 |
1203 | Pastorino F et al. Cancer Res. 2003 Nov 1;63(21):7400-9. | NA | NGRSL | NGR | Neuroblastoma | Endothelial cell | Aminopeptidase N | NA | Five human NB cell lines GI-ME-N, GI-LI-N, HTLA-230, IMR-32, and SH-SY5Y, KS1767 cells | Orthotopic neuroblastoma (NB) xenografts in SCID mice | Homing | Liposomal doxorubicin (NGR-SL[DXR]) | US 2009/0092663A1 |
1222 | Arap W et al. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1527-31. | Chimeric SMSIARL-GG-D(KLAKLAK)2 | SMSIARL | NA | Prostrate cancer | Angiogenic endothelial cell | NA | T7,fUSE5 phage /7mer peptide library | NA | TRAMP (prostate cancer-prone transgenic mice),CD-1 male mice (2-4 months) | Homing | Proapoptotic peptide (KLAKLAK)2 | US 2001/0046498 A1 |
1225 | Janssen ML et al. Cancer Res. 2002 Nov 1;62(21):6146-51. | Dimeric RGD peptide | RGDfK | RGD | Growing tumor | Endothelial cell | Alpha-5 beta -3 integrins | NA | NA | BALB/c mice bearing ovarian carcinoma xenograft | Homing | Indium111 | US 2003/0125243 A1 |
1226 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | PRPGAPLAGSWPGTS | PRP | Melanoma, Pancreatic, Brain cancer | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | Human tumor tissues of islet cells of pancreas, glioblastoma of brain. | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells | Homing | Radionuclide PRP-Lip -Andramycin drug | EP1122262A4 |
1227 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | ADGAPRPGAPLA | PRP | Melanoma | Angiogenic endothelial cell | VEGF | NA | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing | NA | NA |
1228 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | DRWRPALPVVLFPLH | WRP | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing | NA | US 6,753,310 B1 |
1229 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | ASSSYPLIHWRPWAR | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing | NA | US 6,753,310 B1 |
1230 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | DRWRPALP | WRP | Melanoma | Angiogenic endothelial cell | VEGF | NA | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing | NA | NA |
1231 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | IHWRPWAR | WRP | Melanoma | Angiogenic endothelial cell | VEGF-C | NA | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing | NA | NA |
1232 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | AAEWLDAFFVRHVDR | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | US 6,753,310 B1 |
1233 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | GDVWLFLTSTSHFAR | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | US 6,753,310 B1 |
1234 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | GCSVSSVGALCTHV | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | NA |
1235 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | APCCSHLDASPFQRP | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | US 6,753,310 B1 |
1236 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | AQSNFVTWGYNVAV | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | NA |
1237 | Oku N et al. Oncogene. 2002 Apr 18;21(17):2662-9. | NA | RASDVGSDVVPRYPF | NA | Melanoma | Angiogenic endothelial cell | VEGF | M13 phage/15 mer peptide library | NA | 5-week-old C57BL/6 male bearing B16BL6 melanoma cells derived tumor | Homing (Phage display clone) | NA | US 6,753,310 B1 |
1262 | Chen Y et al. Cancer Res. 2001 Mar 15;61(6):2434-8. | NA | CRGDCGGKWCFRVCYRGICYRRCR | RGD | Prostate cancer, Melanoma | Tumor cell and Endothelial cell | Integrins | NA | The TSU human prostate cancer cells, B16 melanoma, nontumorigenic cell lines Cos-7, and NIH-3T3 | CAMs of 10-day-old chicken embryos, C57BL/6 mice bearing B16 melanoma | Homing | Antimicrobial peptide | NA |
1308 | Arap W et al. Science. 1998 Jan 16;279(5349):377-80. | NA | CDCRGDCFC | RGD | Human breast carcinoma | Endothelial cell | Integrin | NA | NA | Mice bearing MDA-MB derived tumors | Homing | Doxorubicin | US20030077818A1 |
1309 | Arap W et al. Science. 1998 Jan 16;279(5349):377-80. | NA | CNGRCVSGCAGRC | NGR | Human breast carcinoma | Endothelial cell | Integrin | M13 Phage/CX3CX3CX3C peptide library | NA | Mice bearing MDA-MB-derived tumors, SLK derived human Kaposi's sarcoma xenografts | Homing | NA | WO06067633A2 |
1310 | Arap W et al. Science. 1998 Jan 16;279(5349):377-80. | NA | NGRAHA | NGR | Human Kaposi's Sarcoma | Endothelial cell | Integrin | M13 Phage/CX3CX3CX3C peptide library | NA | Mice bearing MDA-MB-435derived tumors, SLK cell derived human Kaposi's sarcoma xenografts | Homing | NA | PATENT NO 5536814 |
1311 | Arap W et al. Science. 1998 Jan 16;279(5349):377-80. | NA | CVLNGRMEC | NGR | Mouse melanoma | Endothelial cell | Integrin | M13 Phage/CX3CX3CX3C peptide library | NA | Mice bearing MDA-MB-435derived tumors, SLK cell derived human Kaposi's sarcoma xenografts | Homing | NA | US2009/0257951 A1 |
1318 | Chang DK et al. J Biol Chem. 2009 May 8;284(19):12905-16. | IVO-8 | SNPFSKPYGLTV | NA | Multiple tumor | Endothelial cell | VEGF | M13 phage/15 mer peptide library | SAS (oral cancer), HCT116 (colon cancer), BT483 (breast cancer), Mahlavu (liver cancer),PaCa-2 (pancreatic cancer) ,VEGF-stimulated HUVEC (mimic of angiogenic endothelial cells, surgical samples of human breast cancer | SCID mice | Homing | Liposomal doxorubicin | NA |
1319 | Chang DK et al. J Biol Chem. 2009 May 8;284(19):12905-16. | IVO-24 | YPHYSLPGSSTL | NA | Multiple tumor | Endothelial cell | VEGF | M13 phage/15 mer peptide library | SAS (oral cancer), HCT116 (colon cancer), BT483 (breast cancer),Mahlavu (liver cancer),PaCa-2 (pancreatic cancer) ,VEGF-stimulated HUVEC(mimic of angiogenic endothelial cells,surgical samples of human breast cancer | SCID mice | Homing | Liposomal doxorubicin | US 7,704,953 B2 |
1328 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGPDC | RGD | Prostate, Pancreatic ductal, breast cancer, bone , brain, cervical cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | Nude mice with multiple tumors (prostrate PC-3, PPC1, 22RVI Xenograft), (pancreatic MIAPaCa-2 Xenograft) | Homing | Iron oxide nanoworms, iRGD-linked abraxane | US 2009/0246133A1 |
1329 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDRGPDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
1330 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKTTNC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
1331 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHAGDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | NA |
1332 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHGVEC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1333 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDNLPC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1334 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDNLAC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1335 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDNLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1336 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDSVC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1337 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CSGRGDSLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1338 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGKRGDSIC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1339 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CTGRGDALC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1340 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDSAC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1341 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGENC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1342 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDSPDC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1343 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKGPEC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1344 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDKHADC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1345 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDHAANC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1346 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CRGDAGINC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1347 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CGRGDMPSC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1348 | Sugahara KN et al. Cancer Cell. 2009 Dec 8;16(6):510-20. | NA | CEKRGDSLC | RGD | Prostate cancer | Endothelial cell and tumor cell | Alpha 5 beta 3 and Alpha 5 beta 5 integrins neuropilin-1 | T7 phage / CX7C peptide library | Cultured PPC1 human prostate cancer cells, M21 human melanoma cells | NA | Targeting | NA | US 2009/0246133A1 |
1349 | Park JH et al. Small. 2009 Mar;5(6):694-700. | F3 | KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK | NA | Breast cancer ,Fibrosarcoma | Endothelial cell and tumor cell | NA | NA | NA | Mice bearing human (MDA-MB-435 human carcinoma and HT1080 human fibrosarcoma) xenograft | Homing | Superparamagnetic nanospheres, superparamagnetic IO nanoworms (NWs) | US 7,544,767 B2 |
1359 | Chen B et al. BMC Cell Biol. 2009 Sep 9;10:63. | GX1 | CGNSNPKSC | NA | Gastric cancer | Endothelial cell | NA | NA | HUVEC cultured in tumor-conditioned medium,Gastric cancer cell line SGC7901 | Nude mice | Homing | GX1-rmhTNF alpha labeled with 99TcmO4, Antitumor cytokine rmhTNF alpha | CN1580075, CN1872880 |
1361 | Bieker R et al. Blood. 2009 May 14;113(20):5019-27. | NA | GNGRAHA | NA | Tumor metastasis | Endothelial cell | Aminopeptidase N (CD13) and the integrin Alpha- 5 beta-3 (CD51/CD61) | NA | Human umbilical vein endothelial cell lines activated (HUVECs),human melanoma derived cell line M21 ,The human fibrosarcoma cell line HT1080,human lung cancer cell line A549 (adenocarcinoma) | Mice bearing established human adenocarcinoma (A549), melanoma (M21), and fibrosarcoma (HT1080) | Homing | Truncated tissue factor | US 2007/0032419 A1 |
1400 | Zhao X et al. J Exp Clin Cancer Res. 2007 Dec;26(4):509-14. | NA | CPHSKPCLC | NA | Human colon cancer | Endothelial cells | NA | Phage/7-mer peptide library. | Human umbilical vein endothelial cells (HUVEC), Gastric cancer cell line ,Esophageal cancer cells, Colon cancer cells, Liver cancer cells | BALB/C mice with colon cancer xenograft | Homing | NA | NA |
1401 | Borgne-Sanchez A et al. Cell Death Differ. 2007 Mar;14(3):422-35. | TEAM-VP | GGCRGDMFGC | RGD | Metastiasis in tumor | Angiogenic endothelial cells | Alpha-5 beta- 3 integrins | NA | HUVEC, HMVECd, A375M, MCF-7, MDA-MB-231, HeLa, HT-29, Jurkat, CEM and fresh peripheral blood mononuclear cells (PBMC) | BALB C mice | Homing | FITC, Apoptic peptide | WO96/15811,US 6,458,026 B1 |
1454 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | G3-A9 | PQNSKIPGPTFLDPH | P-(C)-G-P-XXX-D(C)-P | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549 trans, Human breast carcinoma cell line MDA-MB-435, Human prostate carcinoma cell line PC-3M, MDA-MB-435 human breast carcinoma cells on HBME-1 monolayers | NA | Targeting & further studied | NA | NA |
1455 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A3 | SMEPALPDWWWKMFK | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 3 | NA | Targeting | NA | NA |
1456 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A4 | DKPTAFVSVYLKTAL | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 4 | NA | Targeting | NA | NA |
1457 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A18 | APRPGPWLWSNADSV | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 5 | NA | Targeting | NA | NA |
1458 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A19 | GVTDSSTSNLDMPHW | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 6 | NA | Targeting | NA | NA |
1459 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A28 | PKMTLQRSNIRPSMP | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 7 | NA | Targeting | NA | NA |
1460 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-A40 | LYPLHTYTPLSLPLF | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 8 | NA | Targeting | NA | NA |
1461 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-C4 | LTGTCLQYQSRCGNTR | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 9 | NA | Targeting | NA | NA |
1462 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | G3-C9 | AYTKCSRQWRTCMTTH | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans,Human breast carcinoma cell line MDA-MB-435,Human prostate carcinoma cell line PC-3M,MDA-MB-435 human breast carcinoma cells on HBME-1 monolayers | NA | Targeting & further studied | NA | NA |
1463 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | G3-C12 | ANTPCGPYTHDCPVKR | P-(C)-G-P-XXX-D(C)-P | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans,Human breast carcinoma cell line MDA-MB-435,Human prostate carcinoma cell line PC-3M,MDA-MB-435 human breast carcinoma cells on HBME-1 monolayers | NA | Targeting & further studied | NA | NA |
1464 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-C44 | NISRCTHPFMACGKQS | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Saos2 (derived from a human osteosarcoma),Human breast cancer cell lines BT549, express detectable levels of galectin-3 ,BT549trans,Human breast carcinoma cell line MDA-MB-435,Human prostate carcinoma cell line PC-3M | NA | Targeting | NA | NA |
1465 | Zou J et al. Carcinogenesis. 2005 Feb;26(2):309-18. | Clone G3-C60 | PRNICSRRDPTCWTTY | NA | Tumor metastasis | Endothelial cell and tumor cell | Galectin-3 | f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library | Saos2 (derived from a human osteosarcoma),Human breast cancer cell lines BT549, express detectable levels of galectin-3 ,BT549trans,Human breast carcinoma cell line MDA-MB-435,Human prostate carcinoma cell line PC-3M | NA | Targeting | NA | NA |
1474 | Funovics M et al. Neoplasia. 2005 Oct;7(10):904-11. | NA | BCDSDSDITWDQLWDLMK | NA | Human prostrate cancer, lewis lung carcinoma | Tumor cell,endothelial cell | E-selectin | NA | Activated HUVEC, Human prostrate biopsies,llc cell line | Mouse xenograft model of LLC | Homing | FITC , nanoparticle CLIO(Cy5.5) | NA |
1747 | Numata K et al. Macromol Biosci 2012 Jan;12(1):75-82. | F3 peptides | KDEPQRRSARLSAKPAPPKPEPKPKKAPAKK | NA | Breast cancer | Endothelial cell | Nucleolin | NA | MDA-MB-435 melanoma cell line, MDA-MB-231 human breast tumor cell line | NA | Homing | Silk-based ionic pDNA complexes | US 7,544,767 B2 |